I have to put my vote in for the Kinesis Advantage as well. For anyone reading this that might be on the fence about the cost, you will not be disappointed. I was suffering from excruciating pain in my forearms, wrists and fingers. That pain disappeared almost as soon as I started using the Kinesis. For me, the big difference is having a wide split between home rows. This keeps my arms almost completely parallel and alleviates the forearm pain. The key layout is a little funky at first, but what I have realized is that each individual key is positioned exactly where your fingers naturally curl and extend. The other change I made was to add a trackball. I keep the trackball on the left and my regular mouse on the right and switch up usage as often as I can.