Used to be daunting, but for my last few builds I have used some combination of PC Part Picker and the selections from the seasonal TechReport.com guides. Much easier than a couple decades ago when I was a teenager.
Should also be mentioned that the manuals that come with things like motherboards and cases are much more detailed than they used to be.
Should also be mentioned that the manuals that come with things like motherboards and cases are much more detailed than they used to be.