For example, there's evidence that on a population level routine screening for prostate cancer may do more harm than good, because it frequently isn't lethal, and the resulting interventions (often for false positives) can have a negative impact themselves.
> The American study found annual screening did not lower the chances of dying of prostate cancer.
> A recent Johns Hopkins University study found surprisingly high rates of hospitalization after prostate biopsies and a 12-fold greater risk of death in those who develop infections.
> "Yet in order to prevent one death from prostate cancer in the 1,000 men screened for PSA, the number of biopsies would double with 154 additional prostate biopsies, and, of 35 additional prostate cancers diagnosed, 12 additional cases of impotence and three additional cases of incontinence would occur. Thus, the harm from routine PSA testing can have a serious effect on the quality of life of patients and provides additional evidence against the use of organised screening for prostate cancer," he says.
yes recommendation now is not to avoid PSA test but to do PSA tests and do something called 'active surveillance' for low grade disease. Much has changed since 2013.
Sure, but only one bit of evidence.
For example, there's evidence that on a population level routine screening for prostate cancer may do more harm than good, because it frequently isn't lethal, and the resulting interventions (often for false positives) can have a negative impact themselves.
https://www.nbcnews.com/health/health-news/when-prostate-tes...
> The American study found annual screening did not lower the chances of dying of prostate cancer.
> A recent Johns Hopkins University study found surprisingly high rates of hospitalization after prostate biopsies and a 12-fold greater risk of death in those who develop infections.
https://www.sciencedaily.com/releases/2013/09/130929142622.h...
> "Yet in order to prevent one death from prostate cancer in the 1,000 men screened for PSA, the number of biopsies would double with 154 additional prostate biopsies, and, of 35 additional prostate cancers diagnosed, 12 additional cases of impotence and three additional cases of incontinence would occur. Thus, the harm from routine PSA testing can have a serious effect on the quality of life of patients and provides additional evidence against the use of organised screening for prostate cancer," he says.