And Israel's GDP is ~500billion, of which ~25b is spent on defense. So, that 3.8b would be a dent, but not insurmountable.
Economic measures could be a different story, but pulling that lever on an an ally of 75+ years would damage the US's credibility. Not to mention to the domestic impact in the US. I don't think any decision makers weighing national interest would go there.
Plus, if the US successfully isolated Israel, it's highly likely the whole region would be at war in short time. Hard to imagine the West not getting involved again at that point, except now in a significantly worse position.
Economic measures could be a different story, but pulling that lever on an an ally of 75+ years would damage the US's credibility. Not to mention to the domestic impact in the US. I don't think any decision makers weighing national interest would go there.
Plus, if the US successfully isolated Israel, it's highly likely the whole region would be at war in short time. Hard to imagine the West not getting involved again at that point, except now in a significantly worse position.