My current personal site (https://knlb.dev) is built with a single 500 line python file that starts with

  #!/usr/bin/env -S uv run --script
  # -*- mode: python -*-
  #
  # /// script
  # requires-python = ">=3.12"
  # dependencies = [
  #    "pyyaml", "flask", "markdown-it-py",
  #    "linkify-it-py", "mdit-py-plugins"
  # ]
  # ///

The HTML templates & CSS are baked into the file which is why it's so long. flask so that I can have a live view locally while writing new notes.

uv's easy dependency definition really made it much easier to manage these. My previous site was org exported to html and took much more effort.

(With the conceit that the website is a "notebook" I call this file "bind").